The September 25 "View" broadcast will mark the first time the Obamas have appeared together on the one-hour show featuring a team of dynamic women, led by Barbara Walters, discussing the hot topics of the day.
ABC said in a statement that the Obamas would talk about their relationship, family life inside the White House and the November 6 presidential elections on the Emmy Award winning show.
On NBC, the wife of Republican presidential challenger Mitt Romney will be a guest on Leno's on "The Tonight Show," also on September 25, and give her thoughts on family life and the coming election, the network said in a statement.
TV chat shows have become a popular tool for politicians to show their human side. Obama became the first sitting U.S. President to appear on a late-night talk show when he was a guest on "The Tonight Show" in March 2009.
(Reporting By Christine Kearney, editing by Jill Serjeant and Gunna Dickson)